The Saigon Central Post Office was designed by the French architect and railway inspector Alfred Foulhoux, the Chief Architect of the Colony, who lived and worked in Saigon from 1874 AD until his death in 1892.

The Saigon Central Post Office (fig.) was his final work and is widely regarded as his greatest. The building's construction started in 1886 AD and was completed in 1891, and despite maintenance and renovations has kept its original 19th century French colonial touch, though some features, such as the statue of the Greek messenger goddess Iris that once stood in the main lobby, has been removed.

Many deem the architectural style and grandeur of this post office reminiscent of the designs of many of the larger European railway stations of that time.

Perhaps it is no coincidence, since its architect was also a railway inspector, a fact that may have contributed to the overall design.

Original maps painted on the interior walls display the region and the telegraphic lines in use at the time (fig.). Though refurbished with more up-to-date telephones inside, the wooden phone boxes do provide a nostalgic impression.